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Biohet

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Scientic Supervisor / Contact Person

Name and Surname
José Carlos Menéndez

Localization & Research Area

Faculty / Institute
Faculty of Pharmacy
Department
Medicinal Chemistry
Research Area
Chemistry (CHE), Life Sciences (LIF)

MSCA & ERC experience

Research group / research team hosted any MSCA fellow?
No
Research group / research team have any ERC beneficiaries?
No

Research Team & Research Topic

Research Team / Research Group Name (if any)
Biohet
Website of the Research team / Research Group / Department
Brief description of the Research Team / Research Group / Department
The Biologically Relevant Heterocycles (Biohet) group at Universidad Complutense has a broad experience in the design and synthesis of bioactive compounds and has collaborated with many leading pharmaceutical companies and research groups throughout the world. It is attached to the "Innovative Medicine" section of the UCM-UPM Campus of International Excellence.
Research lines / projects proposed
The group has broad interests, and its main research lines are:
(a) Anticancer compounds, either based on the optimization of natural models or designed to bind specific cancer targets, including topoisomerases and the TRPM8 calcium channel, an emerging target in prostate cancer.
(b) Multitarget compounds for other areas of chemotherapy, particularly tuberculosis and leishmaniasis.
(c) Multitarget-directed ligands for neurodegenerative diseases, including Alzheimer"s disease and brain ischemia.
(d) Diversity-oriented synthesis for lead discovery, based on in-house developed domino and multicomponent reactions. Green synthesis.

Application requirements

You can attach the 'One Page Proposal' to enhance the attractiveness of your application. Supervisors usually appreciate it. Please take into account your background and the information provided in Research Team & Research Topic section to fill in it.

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