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Cognition in psychiatric disorders; neurobiological basis for early diagnosis and treatment

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Scientic Supervisor / Contact Person

Localization & Research Area

Faculty / Institute
Faculty of Medicine
Department
Department of Legal Medicine, Psychiatry and Pathology (Psychiatry Area)
Research Area
Life Sciences (LIF)

MSCA & ERC experience

Research group / research team hosted any MSCA fellow?
No
Research group / research team have any ERC beneficiaries?
No

Research Team & Research Topic

Research Team / Research Group Name (if any)
Cognition in psychiatric disorders
Brief description of the Research Team / Research Group / Department
The research group on “Cognition in Psychiatric Disorders” led by Dr. Rapado-Castro (PI) is a multidisciplinary research group with an outstanding national and international trajectory in the field of translational clinical research in cognition in psychiatric disorders, and particularly in early-onset psychosis. Our main focus is to understand brain and cognitive development and its functional implications in health and neurodevelopmental disorders using advanced neuroimaging and AI techniques.

The research group is within the Child and Adolescent Psychiatry Department CAPD, Institute of Psychiatry and Mental Health IPSM, at Hospital General Universitario Gregorio Marañón (HGUGM), which offers specialised mental health care to children, adolescents, and adults in a catchment area of more than 1 million people in the Madrid region; it is attached to the Complutense University of Madrid (UCM) and the CIBER for Mental Health, CIBERSAM. The principal investigator Dr. Marta Rapado (PI) is a Ramon y Cajal Principal Research Fellow and PDI at the Complutense University of Madrid, UCM and at the CAPD, IPSM, HGUGM and CIBERSAM in Spain and Honorary Research Fellow at the Department of Psychiatry, University of Melbourne in Australia (UoM). Thus, the group has access to a variety of research and clinical training, national and international collaborations and enough resources for new research leaders to thrive and to develop.

The group is one of the priority lines (L2) of the research Area 3: "Neuroscience and Mental Health" of the Health Research Institute IIS-IiSGM (Instituto de Investigación Sanitaria Gregorio Marañón, IiSGM) and the CIBER for Mental Health, CIBERSAM. Is integrated in the 3.01. "Neurobiological and psychological underpinnings of mental disorders: neurodevelopmental disorders" URL: https://www.iisgm.com/investigacion/areas-de-investigacion/area-3-neurociencia-y-salud-mental/grupo-1-mecanismos-biologicos-y-funcionales-de-los-trastornos-psiquiatricos-en-adolescentes/); the L5 at the Grupo 1. at the CIBERSAM CB/07/09/0023, URL: https://www.cibersam.es/en/groups/research-group?id=14250); is part of the Psychiatry Group at the Moncloa International Excellence Grouo at the UCM URL: http://www.campusmoncloa.es/hgugm/integrantes; and the Department of Psychiatry at the University of Melbourne, UoM in Australia URL: https://findanexpert.unimelb.edu.au/profile/551436-marta-rapado-castro.
Research lines / projects proposed
Our main focus is 1) the study of the neurobiological mechanisms involved in the development of cognitive symptoms, for the identification of biomarkers and new therapeutic targets that allow early intervention, as well as 2) the provision of effective cognitive treatments in neurodevelopmental disorders. Thus, the group works transversally on the following priority research lines:

Line 1: Cognition (including thought, language and communication disturbances) in psychotic disorders and other neurodevelopmental disorders.
Line 2: Neuroimaging and cognition in early-onset psychotic disorders and other neurodevelopmental disorders.
Line 3: Biochemical mechanisms of inflammation and oxidative stress and cognition in early-onset psychotic disorders and other neurodevelopmental disorders.
Line 4: Psychosocial risk factors and interventions in early-onset psychotic disorders and other neurodevelopmental disorders.
Line 5: Neurobiology and cognition in populations at high risk of developing psychotic disorders.
Line 6: Use of artificial intelligence (AI) and computational analysis to enable analyses of potential relationships among clinical, functional and biological features.

Application requirements

Professional Experience & Documents
- Curriculum vitae- Two Letters of recommendation/referees- Motivation letter
- PhD in a relevant discipline (preferably in Biomedical Engineering, Medicine, Neurobiology, Psychological Sciences) and/or advanced qualifications and experience in the relevant discipline area
You can attach the 'One Page Proposal' to enhance the attractiveness of your application. Supervisors usually appreciate it. Please take into account your background and the information provided in Research Team & Research Topic section to fill in it.

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