SALUVET
Scientic Supervisor / Contact Person
Name and Surname
David Arranz Solís
ORCID (link)
Researcher ID (link)
Localization & Research Area
Faculty / Institute
Faculty of Veterinary Medicine
Department
Animal Health
Research Area
Life Sciences (LIF)
MSCA & ERC experience
Research group / research team hosted any MSCA fellow?
Yes
Research group / research team have any ERC beneficiaries?
No
Research Team & Research Topic
Research Team / Research Group Name (if any)
SALUVET
Website of the Research team / Research Group / Department
Brief description of the Research Team / Research Group / Department
The SALUVET Research Group is part of the Animal Health Department of the Veterinary Faculty of the UCM. It was created in 2000 and was recognized by the Community of Madrid in the first call for research groups (2005). SALUVET's activity has been favorably evaluated on all occasions, always receiving the highest rating. In the last evaluation by the Spanish Agency for Research (AEI) in 2022 the group was rated as an excellent group. The common objective of their scientific programme is the study of various relevant transmissible diseases in animals due to their economic or zoonotic impact, mainly through research in three areas: i) the pathogen-host relationship, variability in virulence and the development of harmonized models (in vitro, in vivo and ex vivo); ii) the development of sensitive and specific diagnostic tools; and iii) the development of safe and effective vaccines and treatments. In recent years, given its extensive experience in these areas, the group has been addressing the study of zoonotic diseases (toxoplasmosis, COVID-19) under the “One Health” concept. The group also carries out an intense training activity at the undergraduate and postgraduate level. Since 2000, 38 doctoral theses have been carried out by the group, co-supervised by several of its members. In addition, the group has trained numerous postdoctoral researchers and laboratory technicians. All of them have obtained the highest qualification, 8 of them obtained the Extraordinary Prize and 2 have been awarded the SYVA Prize for the best doctoral thesis in Animal Health. In 2015, the group created ETCU-UCM SALUVET-innova, S.L., a technology-based company whose corporate purpose is the innovation, development and transfer of new products, processes, materials, technologies and services that can contribute to improving animal health, public health and food safety, as well as animal welfare. SALUVET-innova S.L. collaborates with multinationals in the pharmaceutical sector in the development of new vaccines for relevant diseases in animal production and food safety. SALUVET-innova S.L. has been awarded a NEOTEC project for the development of DIVA vaccines (28-03-2018), the innovative SME seal (4-12-2018) and a RIS3 project from the CM for the development of vaccines (2020-2022).
This group has expertise in cell biology, molecular biology, and high-throughput (-omics) techniques of apicomplexan parasites, and the use of in vitro, ex vivo and in vivo models for these diseases. Their recent studies have focused on the study of: i) T. gondii population in Europe and the phenotypic characterization of a limited number of type II and type III isolates from the Iberian Peninsula; ii) obtention of a unique panel of T. gondii isolates; iii) development of ex vivo models to study pathogen-host interactions at the placental interface; iv) harmonization of pregnant sheep models of infection that have helped to understand key-events during congenital toxoplasmosis, including the description of new pathogenic mechanisms responsible of foetal death.
This group has expertise in cell biology, molecular biology, and high-throughput (-omics) techniques of apicomplexan parasites, and the use of in vitro, ex vivo and in vivo models for these diseases. Their recent studies have focused on the study of: i) T. gondii population in Europe and the phenotypic characterization of a limited number of type II and type III isolates from the Iberian Peninsula; ii) obtention of a unique panel of T. gondii isolates; iii) development of ex vivo models to study pathogen-host interactions at the placental interface; iv) harmonization of pregnant sheep models of infection that have helped to understand key-events during congenital toxoplasmosis, including the description of new pathogenic mechanisms responsible of foetal death.
Research lines / projects proposed
1. Development of in vitro, ex vivo and in vivo experimental models for protozoan diseases in ruminants
2. Development of control tools (drugs and vaccines) for protozoan diseases in ruminants
3. Study of the virulence factors, pathogenesis mechanisms, and biological variability of protozoan parasites
4. Epidemiology and diagnosis of infections caused by protozoan parasites
5. Food-borne zoonoses
2. Development of control tools (drugs and vaccines) for protozoan diseases in ruminants
3. Study of the virulence factors, pathogenesis mechanisms, and biological variability of protozoan parasites
4. Epidemiology and diagnosis of infections caused by protozoan parasites
5. Food-borne zoonoses
Key words
Application requirements
Professional Experience & Documents
Any research doctorate in life science, specifically medicine, veterinary, biology or pharmacology is preferable. Background in tissue culture, molecular biology and in vitro/in vivo models is a plus.
Please submit your CV and letter of motivation to davidarranz@ucm.es
Please submit your CV and letter of motivation to davidarranz@ucm.es
One Page Proposal
You can attach the 'One Page Proposal' to enhance the attractiveness of your application. Supervisors usually appreciate it. Please take into account your background and the information provided in Research Team & Research Topic section to fill in it.
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