Traslational hematology
Scientic Supervisor / Contact Person
Name and Surname
Joaquín Martínez-López
Localization & Research Area
Faculty / Institute
Faculty of Medicine
Department
Hospital 12 de Octubre, Hematology
Research Area
Life Sciences (LIF)
MSCA & ERC experience
Research group / research team hosted any MSCA fellow?
No
Research group / research team have any ERC beneficiaries?
No
Research Team & Research Topic
Research Team / Research Group Name (if any)
Traslational hematology
Brief description of the Research Team / Research Group / Department
The Haematological Malignancies Clinical Research Unit focuses on three main objectives.<br /><br />Molecular research of haematological cancer: the study of cancerinduced changes at the proteomic and genomic levels. We aim to: <br />i) find new genomic and proteomic biomarkers for a better diagnosis of these haematological diseases; <br />ii) identify new molecular alterations as predictors of response to a treatment, for example by study ingminimal residual disease; and <br />iii) study immune mechanisms of cancer control, with a special focus on NK cells.<br /><br />In vitro research:<br />i) establish the effects of new anticancer molecules in in vitro models of the disease; <br />ii) determine the mechanisms of resistance to anticancer drugs.<br /><br />Clinical research: translate preclinical findings to benefit patients through a phase I clinical trials unit.
Research lines / projects proposed
Molecular research of haematological cancer: the study of cancerinduced changes at the proteomic and genomic levels. We aim to: <br />i) find new genomic and proteomic biomarkers for a better diagnosis of these haematological diseases; <br />ii) identify new molecular alterations as predictors of response to a treatment, for example by study ingminimal residual disease; and<br />iii) study immune mechanisms of cancer control, with a special focus on NK cells.<br /><br />In vitro research: <br />i) establish the effects of new anticancer molecules in in vitro models of the disease; <br />ii) determine the mechanisms of resistance to anticancer drugs.<br /><br />Clinical research: translate preclinical findings to benefit patients through a phase I clinical trials unit.
Application requirements
One Page Proposal
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